As demonstrated in Desk I and Fig. two, AS-IV brings about apoptosis primarily because of the mitochondrial-dependent intrinsic pathway and also the death receptor-dependent extrinsic pathway. The intrinsic pathway results in the release of cytochrome cTCMs are commonly Employed in scientific treatment in a number of Asian nations around the world.

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, it is commonly used being an adjuvant of pre-existing therapies with other Chinese medication to deal with disorders. Additionally, curcumenol, as an important Energetic ingredient, is usually combined with the principle chemical elements of other Chinese drugs compounds in preparations of scientific purposes to obtain improved scientific effects

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